protein simple simplesol

Upon receipt, store it immediately at the temperature recommended below. The fast separation time, flexible workflow and high reproducibility makes Maurice a true lab workhorse. Headquartered in Orchard Parkway, San Jose, California, ProteinSimple is helping scientists discover answers to real-world problems through protein and disease research. ProteinSimple recently merged with Bio-Techne, and is now a part of the companys Protein Platforms division. If youre struggling to procure high-quality equipment at an affordable price, consider Excedrs leasing program. ACD branded products will be available on biotechne.com in the near future. Electrophoresis 26:556562. Google Scholar, ProteinSimple (2018) Biosimilar platform methods on maurice. Qty Check Availability. CE-SDS & icIEF iCE Platform |ProteinSimple - Bio-Techne Automated Capillary Electrophoresis: A Technological Renaissance at the Heart of Biopharmaceuticals, Joan Kicks Her Method Development into High Gear with iCE3, View All Products Compatible with Maurice, Download 046-296 RevD Maurice cIEF Method Development Guide web, Download 046-297 Maurice CE-SDS Application Guide revG, Reduced IgG: 25 min, Non-reduced IgG: 35 min, 100 guaranteed, 200 maximum for CE-SDS, 500 maximum for CE-SDS PLUS, 0.05 pI units (for wide range 310 ampholytes), 0.7 g/mL (Native fluorescence) 3.0 g / mL(Absorbance) (Values based on a monoclonal antibody), 0.3 g/mL (Value based on Internal Standard), Maurice - CE-SDS & icIEF iCE Platform |ProteinSimple. Fisher Scientific is always working to improve our content for you. This helps study the tumor microenvironment and derive Immuno-oncology discovery. ProteinSimple SimpleSol Protein Solubilizer for cIEF, 200mL. Part of Springer Nature. These include: (1) nucleoproteins (2) proteoglycans and glycoproteins (3) chromoproteins (4) phosphoproteins (5) lipoproteins and (6) metalloproteins (Murray et al., 2006; Watford & Wu, 2018 ). Humana, New York, NY. R&D Systems, Tocris Bioscience and ProteinSimple branded products are available to purchase through biotechne.com. This is a preview of subscription content, access via your institution. ProteinSimple. Electrophoresis, Western Blotting and ELISA, Chromatography and Mass Spectrometry Reagents, Laboratory Syringe Needles and Accessories, Lab Coats, Aprons, and Other Safety Apparel, Sharps Disposal Containers and Accessories, Classroom Laboratory Supplies and Consumables, Applied Biosystems TaqMan Assay and Arrays Search Tool, Applied Biosystems TaqMan Custom Assay Design Tools, Applied Biosystems Custom qPCR Primers and TaqMan Probes Tool, Chemical Storage and Management Resource Center. https://doi.org/10.4161/mabs.21328, CrossRef Protein analysis tools arent the only thing we lease, though. MAbs 4:578585. Bio-Techne is known for developing, manufacturing, and selling biotechnology and reagents for protein analysis and, through this merger, will now offer ProteinSimples analytical instruments as well. The versatility of the instrument allows the possibility of offering clients rapid alternatives to traditional ID and charge heterogeneity assays. Ella . ProteinSimple is known for manufacturing and supplying analytical instrumentation and consumables for protein research. ", Professor Hermann Wtzig, Privacy Policy. However, we are committed to improving your shopping experience. https://www.proteinsimple.com/literature_download.html?docid=1817, ProteinSimple, a Bio-Techne Brand, San Jose, CA, USA, Jiaqi Wu,Will McElroy,Charles Haitjema,Carsten Lck&Christopher Heger, You can also search for this author in https://doi.org/10.1002/elps.200410075, Siedler M (2011) Implementation of a platform approach for early biologics development. In the absence of a stabilizer, Sample 1 aggregated during analysis by IEF, creating a non-reproducible peak pattern (Fig. It is essential in conducting research in biosimilar characterization, cell and gene therapy, and protein aggregation and particle analysis. The Single Cell Western Technology on Milo allows the user to profile heterogeneity in complex samples, simplify phospho-flow signaling studies, measure protein isoform homogeneity, and more. As they are known to intercellular communicators, they take part in numerous cellular and disease processes. ProteinSimples products and solutions will soon be available on Bio-Technes website to enable consumers to access the brands products and services in one place. Setting the standard in quality research reagents for over 30 years, A trusted leader in quality life science reagents, Your trusted supplier for innovative and high performance life science reagents, Proprietary systems and consumables for simpler, more quantitative and affordable protein analysis, Proprietary RNAscope technology capable of detecting and quantifying RNA biomarkers in situ at single molecule sensitivity, A world leader in developing liquid biopsy based diagnostics, 614 McKinley Place NE Using dTag degradation technology, you can target and degrade any intracellular protein of interest. As the name suggests, the company aims to simplify protein research and help thousands of researchers around the world with their diverse portfolio of protein tools. ProteinSimple offers the worlds first automated Single-Cell Western platform: MiloTM. FAX 612 656 4400. Using exoEASY Maxi Kit by QIAGEN and Simple Western automated Western blotting instrument by ProteinSimple, you can easily perform western blotting-based protein analysis in isolated extracellular vesicle samples. View all citations for the Imaged Capillary Electrophoresis (iCE) platform. By continuing to use this website you acknowledge this and agree to our cookie policy. $135.22 / Each of 1. Eastern North America. For use with Maurice, Maurice C. and iCE3 systems. The product is shipped with polar packs. ACD branded products will be available on biotechne.com in the near future. ProteinSimple also conducts webinars and training sessions to help consumers learn more about their products. Headquartered in Orchard Parkway, San Jose, California, ProteinSimple is helping scientists discover answers to real-world problems through protein and disease research. Ella automates every step of the immunoassay workflow. ProteinSimple | LinkedIn See more. All Rights Reserved. Bio-Techne uses cookies to provide you with a great website experience. R&D Systems, Tocris Bioscience and ProteinSimple branded products are available to purchase through biotechne.com. 11,755 followers. Consider leasing through Excedr to save your lab time and money. Bio-Techne uses cookies to provide you with a great website experience. Electrophoresis 39:20912098. Part of the Methods in Molecular Biology book series (MIMB,volume 2261). There are two platforms that provide high resolution and automated quantitative analysis: iCETM and Maurice. The product range includes Maurice S, Maurice C, iCE3. With a comprehensive range of analytical instruments, ProteinSimple provides its customers an easier, faster, and more affordable way to conduct protein analysis. Compatible Instruments. We also lease a wide variety of lab equipment, from general lab, clinical, and analytical instruments to spectroscopy and biotech equipment. The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. ACD branded products will be available on biotechne.com in the near future. Anal Biochem 534:1923. Technical University of Braunschweig in Germany, "The short run times and easy sample preparation allowed for method development within a day or two. CAS Custom Targeted Protein Degradation Services, Certificate of Analysis (COA) Finder Tool. Am Pharm Rev 14:8791, Loughney JW, Ha S, Rustandi RR (2017) Quantitation of CRM197 using imaged capillary isoelectric focusing with fluorescence detection and capillary Western. The protein tools they have developed hold various applications like protein and antibody characterization, bioprocessing, protein quantitation, stability, and formulation testing in the medical, biotech, life science, and pharmaceutical industries. Toll-free 800 343 7475 Chris Heger, Ph.D. - Director, Applications Science - LinkedIn And because proteins tend to aggregate less at lower concentrations you can reduce or even eliminate urea completely in some of your methods. Maurice affords high-resolution characterization of charge variants by preserving our proprietary imaged capillary isoelectric focusing (icIEF) technology, which has been the go-to method for measuring charge heterogeneity. CAS Not finding your part number? Simple Western Systems help perform serum antibody analysis, and multi-analyte characterization of Humoral response. PubMedGoogle Scholar. Google Scholar, Salas-Solano O, Kennel B, Park SS et al (2012) Robustness of iCIEF methodology for the analysis of monoclonal antibodies: an interlaboratory study. PubMed Your feedback has been submitted. This technical note introduces SimpleSol, a novel and alternative reagent to urea to solubilize proteins for icIEF analysis on iCE and Maurice systems. The on-board sample mixing feature further enhances the ease-of-use, and reduces operator-dependent variability commonly encountered with other systems. All Rights Reserved. PubMed MFI is based on micro-flow imaging that helps you know more about particles in your sample and aids in rapid and robust sample analysis. It allows improved reproducibility, quantitation, throughput, and time to market thereby speeding up the vaccine development workflow. In all tests, more than three injections were performed from a single sample preparation under each condition to observe the reproducibility. View all citations for the Imaged Capillary Electrophoresis (iCE) platform. Micro-flow Imaging (MFITM) technology provides more insights into sub-visible particles like particle population differentiating and classification. Automated Western blotting through Simple Western systems enhances accuracy, ensures quality and delivers results and these can easily integrate with PROTAC Screening assays. USA, TEL 612 379 2956 Dont have the budget to purchase lab equipment outright? If you want to simplify equipment procurement, reduce upfront costs, and protect your equipment against unexpected repairs, join our leasing program and lease your next scientific instrument. Correspondence to 1).In the presence of 2 M urea, the peak pattern of Sample 1 became more reproducible (Fig. To access this literature content please fill out the form below. Please visit our Instrument Citation Database to search our collection of scientific articles that feature our instruments. USA, TEL 612 379 2956 J Chromatogr B Biomed Appl 714:113118. Novus Biologicals branded products are not currently available on biotechne.com and can be found at novusbio.com. All contact information provided shall also be maintained in accordance with our SimpleSol Protein Solubilizer, 200 mL. SimpleSol - a Novel Protein Solubilizer for Capillary Isoelectric However, its not always so simple to procure this kind of instrumentation, as equipment cost can be high and your CapEx budget can be limited. A hands-free, easy to use system that provides highly precise and accurate biomarker detection. ProteinSimple SimpleSol Protein Solubilizer for cIEF, 200mL - Fisher Sci These are easy, high-performing and budget-friendly. Their application is seen in PCR tests for SarsCoV2, Exosomes, Proteomic research, Targeted Protein Degradation and Cancer research. ", Joan Garrison, In one day you can complete your method development, or analyze 48 to 100 samples in one batch. All Rights Reserved. Bio-Techne uses cookies to provide you with a great website experience. Christopher Heger . Google Scholar, Wu G, Yu C, Wang W, Wang L (2018) Interlaboratory method validation of icIEF methodology for analysis of monoclonal antibodies. Besides ProteinSimple, Bio-Technes brands also include Tocrus, Novus Biologicals, and R&D Systems.. To learn more, visit Bio-Technes website. They even have an interactive Simple Western Kit Builder to help in your assay planning. SimpleSol Protein Solubilizer, 200 mL. ProteinSimple branded instruments are available to quote. CAS In this article, we will review ProteinSimples product portfolio and applications of its instruments in various domains of medical research. Compass for iCE, the software package Maurice uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment. For use with Maurice, Maurice C. and iCE3 systems. Methods in Molecular Biology, vol 2261. ProteinSimple branded instruments are available to quote. A broad range of protein therapeutics such as monoclonal antibodies, antibody-drug conjugates (ADCs), and fusion proteins are routinely analyzed by icIEF due to its high resolution and high reproducibility. Please sign in to view account pricing and product availability. (eds) Proteomic Profiling. For research in targeted protein degradation, ProteinSimple has SimpleWestern assays to offer. SimpleSol Protein Solubilizer, 200 mL. Nucleoproteins: These proteins are composed of simple . Copyright 2023 Bio-Techne. https://doi.org/10.1002/elps.201800118, Zhang X, Voronov S, Mussa N, Li Z (2017) A novel reagent significantly improved assay robustness in imaged capillary isoelectric focusing. These contain simple protein combined with nonprotein prosthetic group (Murray et al., 2006). By continuing to use this website you acknowledge this and agree to our cookie policy. Jan 2015 - Oct 20161 year 10 months. In regard to the volume of applicable uses of their products, they are immense. ProteinSimples Simple WesternTM Platform is a fully automated system that provides data on 24 samples in only 3 hours. https://doi.org/10.1002/jssc.201200633, CrossRef Technical Data. J Sep Sci 35:31243129. In a single sequencing run, it can measure total protein expression in thousands of cells. Google Scholar, Wu J, Watson A (1998) Automated sample introduction for an imaged capillary isoelectric focusing instrument via high-performance liquid chromatography sampling devices. "I think that the data we produced [on Maurice] shows excellent quality, due to the precise and reliable Maurice instrument. The range includes FluorChem R (Infrared fluorescence), FluorChem E (Multiplex fluorescence), and FluorChem M (Chemiluminescence). Preparation & Storage. Lease the cutting-edge lab equipment you need, save capital for other parts of your business, and achieve R&D milestones quicker. In one day you can complete your method development, or analyze 48 to 100 samples in one batch.
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