Google Scholar. Br J Ophthalmol. https://doi.org/10.1080/02713683.2018.1493129. Prognostic factors and visual outcome for fireworks-related burns during spring festival in South China. [18] Additionally, AS-OCT has been used to assess CT and ET in full-thickness or lamellar keratoplasty planning, limbal stem cell deficiency, dry eye disease, and others. Edelsten C, Reddy MA, Stanford MR, Graham EM. 2019;23:e37. Ophthalmol. 1990;97:24450. Physiological utility of ultrasound biomicroscopy in the lacrimal drainage system. Shi G, Jiang Z, Deng G, et al. Sun Y, Xie H, Liu J, et al. with near-microscopic resolution (reviewed in [ 2. El Shakankiri NM, Bayoumi NH, Abdallah AH, El Sahn MMF. UBM was effective in identifying iridodialysis, cyclodialysis, angle recession, lens subluxation, and anterior segment foreign body in these patients. [19] [20] [21], Lastly, AS-OCT (with high-resolution or commercially available devices) can be a useful adjunct tool in the diagnosis of ocular surface squamous cell neoplasia (OSSN). https://doi.org/10.1007/s003470070008. 2012;33:e10813. Additional publications utilizing UBM to evaluate the pediatric posterior segment included correlation of scleral transillumination to UBM images for localization of intravitreal injection or sclerotomy site [77] and evaluation for choroidal detachment in the setting of rhegmatogenous retinal detachment [78]. https://doi.org/10.1097/IAE.0b013e31819a5fd8. Covidence was used to manage and detect duplicate references and for screening purposes. The conventional clinical approaches, such as nuclear medicine, computed tomography, magnetic resonance and ultrasound, have been limited to resolutions on the order of millimeters. AS-OCT can also generate up to 10mm corneal diameter CT and ET maps by performing high resolution scans on 8 meridians of the cornea, with automated software that reconstructs the cornea 3-dimensionally. Arq Bras Oftalmol. 2016;20:51922.e4. IEEE Trans Ultrason Ferroelectr Freq Control. Clin Ophthalmol. Ophthalmology. 2009;35:1893905. It can improve detection of invasion to adjacent structure since it is able to identify the posterior margin identification, even in densely pigmented tumors or cases with corneal opacities in anterior chamber tumors. https://doi.org/10.1016/j.ophtha.2011.01.044. the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Value of high-frequency ultrasound biomicroscopy in uveitis | Eye - Nature https://doi.org/10.1016/j.jaapos.2007.06.014. 1990;97:24450. Krema H, Santiago RA, Gonzalez JE, Pavlin CJ. Am J Ophthalmol. Am J Ophthalmol. 2012;16:e30.
Comperative analysis of accuracy between low-frequency ultrasound The remaining 44% of papers evaluated the use of UBM in the setting of ocular trauma. Four decades ago, Pavlin, Sherar, and Foster set out to develop an apparatus to be used in the clinical setting for examining anterior structures of the eye not visible by [then] current techniques. https://doi.org/10.1016/0039-6257(84)90184-x. This page has been accessed 83,215 times. Additional key uses of UBM among pediatric subjects with uveitis were to evaluate causes of hypotony, presence of pars planitis, and to evaluate for toxocara uveitis. CYP1B1-related anterior segment developmental anomalies: Novel mutations for infantile glaucoma and von Hippels ulcer revisited. 2012;250:13738. Ophthalmol Clin N Am. , (UBM)UBM, , UBM, , , , , UBM, , UBM, . Sixty-six studies were separately reviewed as case reports and small series to determine UBM equipment type and diseases of interest. A high-frequency linear ultrasonic array utilizing an interdigitally bonded 2-2 piezo-composite. Ophthalmology. 2013;32:e2530. 2000;118:13291333. [2] This results in resolutions up to 20um axially and 50um laterally, and depth of tissue penetration is 4-5mm. 1994;112:15849. The authors found that UBM was helpful in the making the correct diagnosis and treatment plan in these traumatized eyes [52]. Other reported uses include a general assessment of inflammatory lesions of the iris, ciliary body, pars plana, and peripheral vitreous in infectious, autoimmune, and idiopathic cases. 2007;125:13311335. 2011;118:216671. https://doi.org/10.1136/bjo.2010.195479. 2017;21:e24. https://doi.org/10.1080/13816810.2020.1737946. https://doi.org/10.1001/archopht.118.10.1329. Among small studies, trauma was the most common clinical topic. Data from case-control studies looking specifically at congenital glaucoma are shown in Table3 [19,20,21,22,23,24,25]. Long J, Xiang D, Guo Z, et al. UBM can describe the presence of angle closure glaucoma, which is indicated by irido-corneal contact anterior to the scleral spur. Ophthalmology. CAS Evaluation of the anterior chamber angle in glaucoma: a report by the american academy of ophthalmology. Khan HA, Smith DR, Kraft SP. https://doi.org/10.1007/s004170050248. 2012;154:39-46. The authors declare that they have no conflict of interest. Different types of foreign materials including metal, glass, and organic materials were identified. Br J Ophthalmol. Fujifilm Vevo 3100 VisualSonics Ultrasound A Fujifilm Vevo 3100 VisualSonics ultrasound system is in the Preclinical Imaging Laboratory, outside the specific-pathogen-free (SPF) barrier. Cillino S, Casuccio A, Di Pace F, Pillitteri F, Cillino G. A five-year retrospective study of the epidemiological characteristics and visual outcomes of patients hospitalized for ocular trauma in a Mediterranean area. UBM and AS-OCT are both imaging techniques used to image the AS of the eye. 2016;36:391-400. Spectral-domain optical coherence tomography versus ultrasound biomicroscopy for imaging of nonpigmented iris tumors. J Cataract Refract Surg. Thakur N, Singh R, Kaur S, Kumar A, Phuljhele S, Sukhija J. Ultrasound biomicroscopy in strabismus surgery: Efficacy in postoperative assessment of horizontal muscle insertions. https://doi.org/10.1016/j.jaapos.2011.12.116. BMC Ophthalmol. JLB has grant support from National Cancer Institute of the NIH Award K08CA232344, Hyundai Hope on Wheels, and The Wright Foundation. PubMed 2012;96:10847. 1991;254:1178-1181. 2006;69:3838. High-frequency ultrasonic imaging (ultrasound biomicroscopy) offers unique advantages for these applications. Among the reviewed case reports and small series, 50% of publications focused on iridociliary cysts and 50% evaluated small solid tumors of various subtypes but not including retinoblastoma. Zhang YS, Zhou Q, Zhang J, et al. Role of ultrasound biomicroscopy in the planning for secondary implantation of intra ocular lens in aphakia. Retina. https://doi.org/10.1016/j.jcrs.2014.12.049. J Am Assoc Pediatr Ophthalmol Strabismus. Evaluation of vertical rectus muscles using ultrasound biomicroscopy. Morales J, Chaudhry IA, Bosley TM. Future advancements in both materials science [88] and micromachining (i.e., mechanical dicing, and ceramic layering for middle frequency ocular ultrasound 1035MHz [89]; etching, bonding, and lasering for higher frequency ultrasound fabrication 5065MHz [90, 91]) will likely improve the capability of this element, which is highly dependent on electrical properties. Covidence was used as an initial organizational tool to extract the interventions, outcomes, and population characteristics of each study. Mireskandari K, Ali A, Elbaz U, Strungaru H. Characterizing the phenotypic spectrum of Peters anomaly: from mild to severe disease. Miranda D, Sartori M, Francesconi C, Allemann N, Ferrara P, Campos M. Ferrara intrastromal corneal ring segments for severe keratoconus. 2009;116:172530. Ultrasonic biomicroscopy images of zebrafish eyes were obtained with these transducers which demonstrate the feasibility of high resolution imaging with a performance comparable to optical. 78 Although some concern exists regarding Doppler exposure levels, . Higher frequencies provide higher resolution but the signal is increasingly attenuated . Google Scholar. Pediatric eye disease, and in particular diseases of the anterior segment, can be associated with compromised view through the cornea and disorganized anatomy, two areas where UBM technology is the only available high-resolution imaging modality. 2014;33:84850. Surv Ophthalmol. https://doi.org/10.1097/IAE.0b013e3182561f7c. UBM helps detect. Role of ultrasound biomicroscopy in the planning for secondary implantation of intra ocular lens in aphakia. Google Scholar. Assessment of the safety and efficacy of primary retropupillary fixation of iris-claw intraocular lenses in children with large lens subluxations. Pediatric patients present additional diagnostic challenges. Automatic classification of anterior chamber angle using ultrasound biomicroscopy and deep learning. Darusman KR, Wong IB. In general measurements greater than 15mm were the least accurate [70], suggesting postoperative localization of the lateral and superior rectus may be most difficult to measure using current UBM technology. Br J Ophthalmol. Janet L. Alexander. Indian J Ophthalmol. Nine papers were identified that described the use of UBM in ocular trauma. Only 59% of papers explicitly stated the UBM platform and probe frequency used. Mungan N, Nischal KK, Hon E, MacKeen L, Balfe JW, Levin AV. Correspondence to Outcomes were subcategorized by type of study design, UBM platform used, probe frequency used, clinical application including broad disease category (i.e., glaucoma, trauma, uveitis) and specific disease category (i.e., glaucoma following congenital cataract surgery, traumatic cyclodialysis, and toxocara uveitis), anatomy of interest, and outcomes including the quantitative and qualitative utility of UBM reported. Interestingly, changes of ET have been shown even in subclinical disease and could be a sensitive marker in early and form fruste keratoconus. In order to fully appreciate the quantitative features of UBM imaging in pediatric disease, a sophisticated understanding of normal structural anatomy is essential. Ultrasound devices, which generate high-frequency sound waves, are best known for their imaging powers. https://doi.org/10.1136/bjophthalmol-2013-303662. Studies were eligible if they met the following criteria: (1) use of cohort, case-control, or cross-sectional study design; (2) study population included enrollment of at least four pediatric subjects age 018 years old (inclusion of adults was not grounds for exclusion as long as the minimum pediatric enrollment was met); (3) use of UBM was explicitly stated and results of UBM were reported. 2006;10:721. Li Y, Shekhar R, Huang D. Corneal pachymetry mapping with high-speed optical coherence tomography. Presented to the American Academy of Ophthalmology, Chicago, IL, USA. https://doi.org/10.1016/j.jaapos.2006.01.209. Ultrasound Biomicroscopy (UBM) is a technique primarily used for imaging of the anterior segment (AS) of the eye. Ultrasound biomicroscopy of the eye in cystinosis. https://doi.org/10.1067/mpa.2002.122365. Evaluation of extraocular muscle insertions in the setting of strabismus was evaluated in six studies. Recently several devices have been introduced to measure the CCT such as optical coherence tomography, 19 confocal microscopy, 20 ultrasound biomicroscopy, 6, 21 and the Artemis-2 very high frequency ultrasound scanner (VHFUS). Ultrasound imaging, also called sonography, uses high-frequency sound waves to capture static and moving images inside your body. Kobayashi H, Kobayashi K. Quantitative comparison of Zeiss-Humphrey model 840 and Rion UX-02 systems of ultrasound biomicroscopy. Surv Ophthalmol. 2003;19:64553.
Overview of Ultrasound Biomicroscopy - PMC - National Center for J AAPOS. J AAPOS. PubMed Localising rectus muscle insertions using high frequency wide-field ultrasound biomicroscopy. Angle opening distance (AOD), the perpendicular distance between the trabecular meshwork at a point 500um anterior to the scleral spur, and the iris. Pavlin CJ, Sherar MD, Foster FS. https://doi.org/10.1590/s0004-27492006000300018. The screening process as well as exclusion reasons are illustrated in Fig. https://doi.org/10.1136/bjophthalmol-2011-301016. Key findings from these studies include: (1) AS-OCT and UBM can be used interchangeably for corneal thickness and depth measurements in patients with CCO [53], (2) in cases of CCO with penetrating keratoplasty histopathological correlation, UBM diagnosis was correct 100% of cases while clinical diagnosis prior to UBM was correct in 62% of cases [54], (3) UBM informs genotypephenotype correlations [54], (4) UBM assisted in both diagnosis and treatment decisions for CCO [55,56,57,58,59]. https://doi.org/10.1016/j.jaapos.2019.08.132. S27 to S29 and movies S3 and S4; see materials and methods for details on acoustic simulation). Surgical planning or evaluation of surgical results related to predicting surgical outcomes and risk factors, monitoring blebs, and integrating structural information into surgical plans was performed. Intraocular mass lesions are key pediatric diseases evaluated using UBM. Emery J, Ho D, Mackeen L, Hon E, Bissonnette B. Pupillary reflex dilation and skin temperature to sensory level during combined general and caudal anesthesia in children. Ludwig K, Wegscheider E, Hoops JP, Kampik A. Optical coherence tomography and ultrasound biomicroscopy imaging of opaque corneas.
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